Scientists Spot Clue to Cancer's Aggressiveness

(HealthDay News) -- Researchers say they have gained insight into whether certain aggressive cancers -- including those that attack the pancreas, breast and skin -- will respond to a certain anti-cancer drug.

The key appears to lie in a molecular signature inside tumors, researchers reported in the Sept. 6 online issue of Nature Medicine.

Researchers at the University of California, San Diego, found that a receptor on the surface of some tumor cells can start a process that leads cells to become more aggressive. An anti-cancer drug called dasatinib (Sprycel), approved for treating a form of leukemia, blocks the process.

Researchers say figuring out whether the receptor exists on tumor cells could indicate whether the tumors might respond to the drug. Read more...

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