Thursday, August 26, 2010

Calorie restriction, exercise rejuvenate nerve connections

An article published this week in the Proceedings of the National Academy of Sciences (http://www.pnas.org/) reveals a mechanism for exercise and calorie restriction in delaying some of the effects of aging.

In their introduction, Joshua R. Sanes and his Harvard University colleagues explain that "The cellular basis of age-related behavioral decline remains obscure but alterations in synapses are likely candidates. Accordingly, the beneficial effects on neural function of caloric restriction and exercise, which are among the most effective anti-aging treatments known, might also be mediated by synapses."

Synapses are the connections that exist between nerve cells or nerves and the muscles that they control. The current research compared a synapse known as the skeletal neuromuscular junction in young adult and aged mice. Read more...

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