Clinical experience with EDTA chelation therapy has convinced substantial numbers of licensed physicians in North America that it is a safe and effective treatment for atherosclerotic vascular disease, as it consistently improves blood flow and relieves symptoms associated with the disease in greater than 80% of the patients treated. As members of the medical profession are generally aware, the pathogenesis of atherosclerotic disease is extraordinarily complex. The scientific principles underlying the efficacy of EDTA chelation therapy in impeding each step of the disease process are beyond the scope of this discussion, but they are elaborated upon in the many published clinical studies and research papers available.
In its simplest terms, the rationale for its efficacy is that EDTA, in binding ionic metal catalysts and removing them from the body, reduces subsequent abnormal production of oxygen free radical reactive molecules and molecular fragments which react destructively with other molecules.
There is now widespread agreement that EDTA removes metallic catalysts which cause excessive oxygen free radical proliferation, thereby reducing pathological lipid peroxidation of cell membranes, DNA, enzyme systems and lipoproteins and allowing the body's natural healing mechanisms to halt and often reverse the disease process.
Steinberg, et al., state in the April 6, 1989, New England Journal of Medicine, 1989; 320(14): 915-924, concerning Modifications of Low-density Lipoprotein That Increase Its Atherogenicity through free radical peroxidation, "oxidative modification is absolutely dependent on low concentrations of copper or iron in the medium and is therefore completely inhibited by ethylenediaminetetraacetic acid (EDTA)."
Chelation therapy is considered by the physicians who utilize it to be an effective first step alternative to surgical treatment for atherosclerotic vascular disease in most cases.
Vascular disease is a leading killer globally and it results in loss of circulation to affected parts of the body with at times severe debilitation or death.
The signs of vascular disease appear:
- On the legs as loss of hair, thinning and atrophy of the skin, non-healing sores, or even blackened toes from gangrene, and pain on exercise.
- In the heart, the signs are pain or pressure in the chest, shortness of breath or unusual fatigue.
- In the brain, causing loss of memory and confusion, momentary lapses of consciousness (sometimes called a TIA, or transient ischemic attack), or eventually strokes.
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