The CDC Vastly Underestimates the Autism Epidemic

The Center for Disease Control (CDC) states that 1 in every 150 children has an autism spectrum disorder. But a report from the Vaccine Autoimmune Project puts the autism prevalence at 1 in every 67 children, based on Department of Education statistics.

Even that report only includes children who qualify for special education services through the autism eligibility category, and therefore potentially excludes thousands of children.

A recent report from the military also confirmed this number; there are more than 22,000 people service wide with a diagnosis of an autism spectrum disorder, almost all of them children of active duty or retired active duty dependents.

The numbers come to about 1 in 88 children of active duty personnel, and 1 in 47 retired active duty dependents, with a combined average of, once again, 1 in 67 military dependent children with autism.
Sources:
Vaccine Autoimmune Project July 10, 2008

Jim Adams, Autism & Chelation on Dateline NBC pt 1

Jim Adams, Autism & Chelation on Dateline NBC

Mercury in Childhood Vaccines Excreted Quickly

(HealthDay News) -- The latest chapter in the debate over whether childhood vaccines can cause autism was written Wednesday with release of a study that showed the controversial mercury-containing preservative thimerosal is rapidly excreted from babies' bodies and can't build up to toxic levels.

"Thimerosal has been used for decades, but the surge in vaccinations caused fear that possible accumulations of ethyl mercury, the kind in thimerosal, might exceed safe levels -- at least, when based on the stringent risk guidelines applied to its better-understood chemical cousin, methyl mercury, which is associated with eating fish," lead researcher Dr. Michael Pichichero, professor of microbiology/immunology, pediatrics and medicine at the University of Rochester, said in a prepared statement.

"One of the unanswered questions when this first popped up as a controversy was, when you got thimerosal as an injection, how long would it stay in your blood," co-author Dr. John Treanor, a professor of medicine at the University of Rochester Medical Center, said in an interview.

The new research, he added, showed that "the levels of thimerosal don't go very high and they go down right away. By the time it's time for the next dose of vaccine, the levels are right back to where they were at the beginning."

For their study, Pichichero's team tracked 216 infants from R. Gutierrez Children's Hospital in Buenos Aires, Argentina, where thimerosal is still routinely used in vaccines. Use of thimerosal in childhood vaccines was discontinued in the United States after a joint decision in 1999 by U.S. health officials, pediatricians and vaccine manufacturers.

The infants in the study were put into three age groups and their blood-mercury levels were tested both before and after vaccinations were given to newborns, and at their two- and six-month checkups.

Pichichero's group found that for all three age groups, the half-life of ethyl mercury in the blood -- the time it takes for the body to get rid of half the mercury, and then another half, and so on -- was 3.7 days. That's significantly less than the half-life of methyl mercury, the kind found in fish, at 44 days.

"Until recently, that longer half-life was assumed to be the rule for both types of mercury. Now it's obvious that ethyl mercury's short half-life prevents toxic build-up from occurring. It's just gone too fast," Pichichero said.

"If you thought thimerosal was responsible for autism, you would be looking at mercury levels that were far below anything anyone's previously thought as being toxic," Treanor added.
"Though it's reassuring to affirm that these immunizations have always been safe, our findings really have greater implications for world health," Pichichero said. "Replacing the thimerosal in vaccines globally would put these vaccines beyond what the world community could afford for its children."

The study findings were to be released Monday in the February issue of the journal Pediatrics. But they were released early by the American Academy of Pediatrics, which is requesting that the ABC network cancel the premiere episode of a new show Thursday dealing with the thimerosal-autism controversy.

The new findings also follow a recent report from the California Department of Health that rates of autism continue to climb there even after thimerosal was removed from childhood vaccines.

And they follow a series of studies, including a large-scale U.S. Institute of Medicine review in 2004, that failed to uncover a link between childhood vaccines and autism. The first report of a possible connection appeared in British study in the late 1990s and has since been discredited.

Current estimates by the U.S. National Institutes of Health say that one American child in 150 has been diagnosed with autism, although experts wonder if that increase owes to better diagnoses and a broader definition of the disorder.

Still, at least one vaccine critic worries that inoculations are making children prone to autism, a developmental disorder characterized by impaired social interaction, communication problems, and unusual, repetitive, or severely limited activities and interests. And if it's not thimerosal, then it must be some other vaccine-related interaction, said Barbara Loe Fisher, co-founder and president of the National Vaccine Information Center.

"There are many biological mechanisms involved in vaccine-induced brain and immune system changes that could quite well lead to autism," she said.

"Mercury doesn't belong in any product," Fisher added. "Mercury doesn't belong in vaccines whether it's proven or not proven that mercury is a problem in vaccines."

In ABC's new TV series Eli Stone, the premiere Thursday focuses on a lawyer arguing that a vaccine caused a child's autism. While the show includes statements that science has refuted a link between autism and vaccines, the program reinforces the connection as the jury awards the mother $5.2 million, according to the AAP.

"If parents watch this program and choose to deny their children immunizations, ABC will share in the responsibility for the suffering and deaths that occur as a result. The consequences of a decline in immunization rates could be devastating to the health of our nation's children," AAP President Dr. Renee R. Jenkins said in a prepared statement.

More information
For more on thimerosal and autism, visit the The Children's Hospital of Philadelphia.

Gene Plays Role in Risk of Autism

(HealthDay News) -- A gene that appears to play a key role in the development of autism has been identified by three different teams of researchers.

UCLA scientists found that the gene -- contactin-associated protein-like 2 (CNTNAP2) -- is most active in brain regions involved with language and thought and that the presence of the gene may explain speech delays in children with autism.

Their study appears in the Jan. 10 online edition of The American Journal of Human Genetics.

The same issue also features reports from research teams at Johns Hopkins University and Yale University that link the CNTNAP2 gene to autism. Meanwhile, a consortium of autism researchers from the Boston area reported in the Jan. 10 issue of the New England Journal of Medicine that abnormalities on chromosome 16 seemed to raise the risk of a certain kind of autism.

The UCLA scientists noted that the gene they discovered is tied closely to language development.

"This gene not only may predispose children to autism. It also may influence the development of brain structures involved in language, providing a tangible link between genes, the brain and behavior," principal investigator Dr. Daniel Geschwind, a professor of human genetics at UCLA's David Geffen School of Medicine, said in a prepared statement.

In the study, researchers analyzed DNA samples from almost 500 families that had at least one autistic child and found that CNTNAP2 showed up consistently in the samples.

The UCLA team also examined CNTNAP2 presence in early brain tissue and found that the gene was most active in developing brain structures involved in language and thought.

Researcher Brett Abrahams, a postdoctoral fellow, explained the significance of the finding by comparing the brain to a house.

"We know that different rooms in houses serve different purposes. For example, if an item only appears in the kitchen, it makes sense to assume it's involved in cooking. Or if we find an object only in the bedroom, it's likely connected to sleeping," he said in a prepared statement. "The fact that we found CNTNAP2 concentrated in the brain's structures that are involved in higher cognition gives us strong clues about how its disruption might adversely shape brain development, including speech and language."

The UCLA researchers also found that the gene was strongest in families with autistic boys, compared to families with autistic boys and girls or families with autistic girls only.

"Autism strikes boys three times as often as girls," Maricela Alarcon, first study author and an assistant professor in residence of neurology at UCLA, said in a prepared statement. "This finding may partly explain why."

In the Johns Hopkins study, researchers found that a specific variation in the structure of CNTNAP2 makes a child more vulnerable to developing autism. They looked at more than 1,300 children with autism and their parents and found that where a single segment of the genetic code of CNTNAP2 could contain either the chemical base adenine or thymine, children with autism tended to have the thymine variant.

The researchers also found that children with autism were about 20 percent more likely to have inherited the thymine variant from their mothers than from their fathers.

"This is a common variant. People inherit it all the time. Our finding that it's associated with autism more often when it's inherited from mothers is intriguing, but needs to be replicated," Johns Hopkins researcher Aravinda Chakravarti said in a prepared statement.

More information
The U.S. National Institute of Neurological Disorders and Stroke has more about autism.

Autism's Rise May Reflect Broader Definition, Better Diagnosis

(HealthDay News) -- How widespread is Autism? And is the condition, which centers on characteristics such as the inability to form personal relationships, being properly diagnosed?

New York City-based YAI-National Institute for People With Disabilities (YAI-NIPD) is a not-for-profit organization that not only assists families who have members with a variety of developmental disabilities, but also holds a series of conferences that highlight the latest research into specific conditions.

Earlier in May, YAI-NIPD held an autism conference that addressed the apparent increase in autism cases. One reason may be a broader definition of autism, said Dr. David Kaufman, medical director of Premier Healthcare, a Manhattan organization specializing in disability services.

"The estimate was one child in 166, made by the epidemiology unit of the [U.S. governments] National Institutes of Health," Kaufman said. "Now it is down to one in 150. I think that since the definition has been broadened, a lot of children are getting diagnosed who are at the milder end of the spectrum."

The cause of autism remains unclear, Kaufman said. "I believe that there is something in these children that predisposes them to autism and maybe something that triggers it, perhaps a viral illness, like children who get diabetes at an early age."

Whatever the cause, "the best treatment so far is diagnosing it early on and intervening early on, sometimes with medications," Kaufman said. "There is a broad array of early intervention services."

When a child's mysteriously detached behavior arouses parents suspicions, "the first line of defense is with the pediatrician," he said. "The child can be referred to a developmental pediatrician or pediatric neurologist or specialist who will do an evaluation and then send the child to a speech therapist, a language therapist or another therapist for treatment. The earlier you intervene, the better children do."

Financial help is often available from state governments, but "each state has different funding lines," Kaufman noted.

Children's basic medical needs should not be overlooked, Kaufman said. "Their medical needs are the same as anyone else, but it is harder to get at them," he said. "Once they get to age 2 or 4, they are able to tell the doctor what is wrong with them, but they are not as cooperative as another child might be."

Although there is a long way to go, "One thing that is being done right is an increased awareness of autism," said Dr. Eric Hollander, professor and chairman of psychiatry at Mount Sinai School of Medicine in New York. "It has become a priority funding issue for the National Institutes of Health. There are findings that directly impact on treatment and also can lead to a better understanding of the underlying causes."

One area that clearly has been neglected is autism in adults, Hollander said. "The high school or college population, the need for residential care is also there. Child psychiatrists and pediatricians will not necessarily be treating these individuals when they get older.

"And those who work with the older population don't have enough training. We need to know a lot more about intervention with medication, how it alters outcome, the repetitive behavior, the rigid behavior, and also new treatments for disruptive behavior."

What causes autism? Attention is being focused on oxytocin, a hormone produced by the pituitary gland, Hollander said. It appears to play a role in social behavior and repetitive behavior. "Now we are starting to have a certain impact on symptoms by administering oxytocin in various forms, such as intravenously."

Attention also is being paid to environmental and genetic factors, Hollander said, "things in the environment that influence what genes are turned on and turned off. We need to know a lot more about environmental factors and how they play a role in some people with autism."

One indicator of how much remains to be learned is the widely differing rates of diagnosis of autism from state to state, Hollander said, but that is just part of the picture. "We don't have predictors of which individuals will respond to which kinds of treatment," he said, but ended on a hopeful note: "With additional funding, there will be more rapid breakthroughs."

Dr. Steven Lowe, the medical director of YAI-NIPD, added that autism treatment still is often a struggle. "It's a challenge, because so little work has been done in the management of patients with autism and also in mental retardation and developmental disabilities," he said. "There has been very limited work on management of such patients in the primary care area and very limited research. There is limited interest for primary health-care practitioners, because it is such a daunting prospect."

But there is impetus for progress from "parents and other caregivers and the media," Lowe said. "Among them, the issue of autism is better recognized, and it is less of a stigma. People with autism are becoming more visible. Caregivers are advocating for better access to the same sort of health care that disabled people are getting.

"There is a tremendous lack of formalized training in medicine appropriate to this patient population," Lowe added. "But there are providers out there -- institutions like our own take care of patients with mental disabilities, mainly through on-the-job training."

For families facing a problem, "my recommendation is to find a place that specializes in this patient population," Lowe said. "Look for a multidisciplinary system where everyone is comfortable with mental retardation or developmental disabilities such as autism. You need a large group of clinicians in various fields, the kind of team approach that has proven to be very effective."

Then there is the influence of other elements, such as diet. Dr. Joseph Levy, a pediatric gastroenterologist who is professor of pediatrics at the New York University School of Medicine, offers a theory that developmental disability is often literally a gut issue.

"There are a whole host of anecdotal reports about how particular diets have enabled children to make progress," Levy said. "Sooner or later, every parent will focus on the dimension of nutrition of child care and will experiment with it. For example, if there is aggressive or self-injurious behavior, the explanation is that the child has reflux irritation or difficulty with bowel movements."

The problem is that parental concentration on dietary factors means that they "sometimes are committed to thinking that autism is the manifestation of a leaky gut," Levy said. "But we don't know whether it is proven that autism is really a disease that affects the immune system in the gut, with toxins that are absorbed from the intestines."

It is necessary to work with nutritionists to be sure that children with autism get the proper micronutrients, but "autism is not one diagnosis, and this can put parents to great restrictions and might even be harmful," Levy said. "We do have to move forward the science that enables us to understand what is going on in the gut of the child, but we must do that without a preset ideology."

More information
There's more on autism at Autism Speaks.

A Comprehensive Review of Heavy Metal Detoxification and Clinical Pearls from 30 years of Medical Practice by Dietrich Klinghardt, MD.,Ph.D

A. Introduction:
Heavy Metals appear in the mammalian system because they have become part of our environment.

We are in a constant exchange with our environment which is goverened by the laws of osmosis.

If mercury is in the fish we eat, over time we have mercury in our system. We cannot keep our system pristine and clean, because we are seperated from our toxic environment only by semi-permeable membranes: skin and mucosal surfaces.

Maintaining relative cleanliness requires a number of inherentdetox systems to work overtime against the osmotic pressure of the incoming toxins. As the toxixity of our environment increases so does the osmotic pressure, pushing the often man- made poisons into our body.

Toxins almost never come alone. They come in synergistically acting package-deals. Mercury alone is toxic. Together with zinc it is many times more toxic, add in a little copper and silver, as in dental amalgam fillings and the detrimental effect to the body increases manyfold.

Together with mercaptan and thioether (dental toxins) the toxic amalgam effects grow exponentially.

Add in a little PCB and dioxin, as in fish, and the illness causing effect of the methyl mercury in fish increases manyfold. Toxicology is to a large degree the study of synergistic effects.

In synergy 1 plus 1 = 100. Heavy metals are primarily neurotoxins. There is a synergistic effect between all neurotoxins which is responsible for the illness producing effect.

Making the neurotoxin elimination a major part of my practice has been an amazing experience.

Many illnesses considered intractable respond when the related issues are successfully resolved.

What are Neurotoxins?

Neurotoxins are substances attracted to the mammalian nervous system. They are absorbed by nerve endings and travel inside the neuron to the cell body. On their way they distrupt vital functions of the nerve cell, such as axonal transport of nutrients, mitochondrial respiration and proper DNA transcription. The body is constantly trying to eliminate neurotoxins via the available exit routes: the liver, kidney, skin and exhaled air.

Detox mechanisms include acetylation, sulfation, glucuronidation, oxidation and others. The liver is most important in these processes. Here most elimination products are expelled with the bile into the small intestine and should leave the body via the digestive tract. However, because of the lipophilic/neurotropic nature of the neurotoxins, most are reabsorbed by the abundant nerve endings of the enteric nervous system (ENS) in the intestinal wall. The ENS has more neurons than the spinal chord. From the moment of mucosal uptake the toxins can potentially take 4 different paths:

1. Neuronal uptake and via axonal transport to the spinal chord (sympathetic neurons) or brainstem (parasympathetics) – from here back to the brain.
2. Venous uptake and via the portal vein back to the liver
3. Lymphatic uptake and via the thoracic duct to the subclavian vein
4. Uptake by bowel bacteria and tissues of the intestinal tract

i) Heavy metals:
mercury, lead, cadmium, iron, manganese and aluminum (are the most common).Common Sources: metallic mercury vapor escapes from dental amalgam fillings (they contain about 50% mercury, the rest is zinc, silver copper, tin and trace metals). Cadmium: car fumes, cigarette smoke , pigment in oil paint Lead: outasing from-paint, residues in earth and food chain from time when lead was used in gasoline, contaminated drinking water Aluminum: cookware, drinking water

ii) Biotoxins:
such as tetanus toxin, botulinum toxin (botox), ascaridin (from intestinal parasites), unspecified toxins from streptococci, staphylococci, lyme disease, clamydia, tuberculosis, fungal toxins and toxins produced by viruses. Biotoxins are minute molecules (200-1000 kilodaltons) containing nitrogen and sulfur. They belong to a group of chemical messengers which microorganisms use to control the host´s immune system, host behaviour and the host´s eating habits.

iii) Xenobiotics (man-made environmental toxins):
such as dioxin, formaldehyde, insecticides, wood preservatives, PCBs etc.
iv) Food Preservatives, excitotoxins and cosmetics:
aspartame (diet sweeteners), MSG, many spices, food colourings, fluoride, methyl-andpropyl -paraben, etc.

Heavy Metal Toxicity
Metals can exist in the body with different kinds of chemical bonds and as different molecules. Mercury appears to be the king-pin in the cascade of events in which metals become pathogenic. Mercury can be present as metallic mercury (HgO), as mercury salt (e.g. mercury chloride – HG+), or as methyl mercury (HG++). Methyl mercury is 50 times more toxic than metallic mercury. Methyl-Hg is so firmly bound to the body that it has to be first reduced to HG+ before it can be removed from the cell. This is achieved with reducing agents (“antioxidants”) e.g. intravenous vitamin C and reduced glutathione.

To remove Hg-Salts or metallic Hg from the outside of the cell, other agents are useful Mercury belongs to a group of metals that oxidize in the presence of sulfur and form compounds with sulfur (sulfhydryl affinitive metals). Methyl mercury is already oxidized to its maximum and bound firmly to sulfur in the different proteins of the body. The following metals belong to the sulfhydryl affinitive group and respond to similar detoxification methods: Copper, arsenic, cadmium, lead, mercury. Aluminum and iron for example would not respond a sulfur compound. Some detox agents have multiple mechanisms by which they bind to metals. The algal organism chlorella has over 20 known such mechanisms.

Other metals oxidize with oxygen. Iron turns to rust when oxidized. Rust is nontoxic to the body, whereas iron is. Iron overdose responds to a chemical called desferoximin (desferal). Aluminum responds to the same detoxification agent. A recent Japanese study showed that Chinese parsley, cilantro, is a powerful elimination agent for aluminum stored in bone and the brain.

Other facts:
· Some metals are extremely toxic, even in the most minute dose, whereas others have very low toxicity, even in high doses. However, dependent on the dose, all metals can become toxic to the body. Iron can cause severe oxidative damage, copper may compromise liver function and visual acuity, selenium and arsenic have been known to be used to murder people and so on.
· Most metals serve a functional role in the body. For example, selenium is needed in the enzyme that restores oxidized glutathione back to its functional form as reduced glutathione. Another important function of selenium is its role as a powerful antioxidant in preventing cancer.
· Some metals have a narrow physiological range. That means the difference between a therapeutic dose and toxic overdose is very small. Selenium is an example of this. Magnesium on the other hand has a wide physiological range and thus is more difficult to overdose.
· Some metals have no physiological function. Mercury, lead, aluminum are in this group. Even the smallest amounts have negative physiological-effects.
· biochemical individuality: some people may react more or less than others to the presence of heavy metals in the tissues. Some people may develop a severe chronic illness after exposure of a few molecules of mercury, whereas others may be more resistant to it. Genetic deficiencies in the enzymes responsible for the formation of the metallothioneins and glutathione production and reduction are examples.

Possible side-effects during heavy metal detox:
Every patient can be affected by metals in two ways:
1. Through their non-specific toxic effects
2. Through the system´s allergic reactions to the neurotoxins
Often these two distinctive types of symptoms cannot be easily distinguished. During a detox program, the patient may also temporarily become allergic to the various substances that help to carry out the toxins. This is based on a physiological mechanism called ‘operant conditioning’.

Every time the detoxifying substance is given, mercury emerges from its hiding places into the more superficial tissues of the body, where mercury can now be detected by the immune system. The immune system however is fooled into thinking that the detoxifying substance itself is the enemy. The immune system now starts to react to the detoxifying substance as if it was the mercury itself. This reaction typically resolves spontaneously after six weeks of not using the detox agent in question. This type of conditioned reflex can also be easily treated with simple techniques e.g. NAET, PK (APN), or by giving the detox substance in a homeopathic dilution for a few days. Often the basal membranes in the kidney will swell as a sign of the allergic reaction, causing low back pain, anuria or inability to concentrate urine.

Neuraltherapy or microcurrent stimulation of the kidneys quickly resolves the issue. Muscle aches indicate the redistribution of toxins into the connective tissue and an insufficient program. Depression, headaches, trigeminal neuralgia, seizures, increased pain levels indicate redistribution of metals into the CNS and an inappropriate detox program. Eye problems and tinnitus that occurs during detox indicates redistribution of metals into these organs and requires selective mobilization from these locations before the program is continued. I use a specific type of microcurrent for this purpose

Some recently published findings related to the metal issue:
Iron/mangnese: A recent paper on Parkinsons disease (Neurology June 10, 2003;60:1761-1766)revealedthat just by eating iron and manganese containing foods such as spinach or taking supplements containing Mn or Fe - the risk of developing PD increased almost 2 fold. This demonstrates that even dietary supplements or organically grown foods are amongst the possilbe culprits in metal toxixity.

Methylmercury:
There are two major sources:
1. mercury escaped from dental amalgam fillings is converted by oral and intestinal bacteria to methylmercury, which then is bound firmly to proteins and other molecules. Methyl mercury crosses the blodd brain barrier and the placental barrier leading to massive prenatal exposure. Earlier studies determined that over 90% of the common body burdon of Hg is from dental fillings. Recent studies show that eating fish is starting to compete with amalgam fillings for the leading position as a risk factor.
2.Seafood
A recent study (JAMA, April 2, 2003;289(13):1667-1674) revealed the following It is estimated that nearly 60,000 children each year are born at risk for neurological problems due to methylmercury exposure in the womb. One in 12 U.S. women of childbearing age have potentially hazardous levels of mercury in their blood as a result of consuming fish, according to government scientists. The U.S.FDA recommends that pregnant women and those who may become pregnant avoid eating shark, swordfish, king mackerel, and tile fish known to contain elevated levels of methylmercury, an organic form of mercury. Nearly all fish contain some amount of methylmercury. Mercury accumulates in the system, so larger, longer-lived fish like shark or swordfish contain the highest amounts of mercury and pose the largest threat if eaten regularly.
The National Center for Policy Research for Women & Families published in May 2003, that the following fish are lowest in methyl mercury:
· Catfish (farmed)
· Blue Crab (mid-Atlantic)
· Croaker
· Fish Sticks
· Flounder (summer)
· Haddock
· Trout (farmed)
· Shrimp
The FDA also recommends these fish as safe to eat:
haddock, tilapia, wild alaskan salmon,and sole

Ethylmercury:
A recent quote from Boyd Haley, PhD: “our latest research clearly points to the ethylmercury exposureas being causal in autism. The tremendous enhancement of thimerosal toxicity by testosterone and the reduction of toxicity by estrogen explains the fact that 4 boys to 1 girl getting the disease and the fact thatthe bulk of severe autistics are boys. Most importantly, this autistic situation clearly shows that exposureto levels of mercury that many "experts" considered safe was capable of causing an epidemic of a neurological disease”.

B. Symptoms
Other authors have tried to specify typical symptoms for each metal. Because of the synergistic effects and simultaneous occurence of several toxins at the same time. The best source of literature on the effects of specific metals on the system are the old homeopathic textbooks ‘materia medica’ (Kent, Boericke).

I prefer to look at a client in a systemic way, not focussing on single issues . A manganese typical symptom (ie violent behaviour) may be a lot more worrysome in a given patient then their particular mercury related symptom (ie insomnia). However, the practical focus of detox should be almost always on the mercury first. If mercury is adressed appropriately, the manganese often leaves the body as a side effect of mercury detox. The opposite is not true.
Any illness can be caused by, or contributed to, or exagerated by neurotoxins. Here is a short list:
· Neurological problems: Fatigue, depression, insomnia, memory loss, blunting of the senses, chronic intractable pain (migraine, sciatica, CTS etc.), burning pain, paresthesia, strange intracranial sensations and sounds, numbness. Autism. Seizure disorder. Hyperactivity syndromes. Premature ejaculation and inorgasmia
· Emotional problems: inappropriate fits of anger and rage, timidness, passivity, bipolar disorder, frequent infatuation, addictions, depression, dark mood, obsession, psychotic behaviour, deviant behaviour, psychic attacks, inability to connect with god, etc.
· Mental problems: memory loss, thinking disorder, messy syndrome (cluttering), loss of intelligence, AD, premature aging
· GI problems: candida, food allergy, leaky gut syndrome, parasites, inflammatory bowel disease
· Orthopedic problems: joint arthritis, persisiting musculo-skeletal pain, fibromyalgia, TMD,recurrent osteopathic lesions
· Immunological disorders (autoimmune diseases, hypothyroid disorders, MS, ALS, Sjogen´s Syndrome, CFIDS, MCS etc.)
· Cardiovascular disorders ( vascular disease, arrythmias, angina, increased heartbeat)
· Cancer –mercury, arsenic, copper etc. can be a trigger
· ENT disorders: chronic sinusitis, tinnitus, glandular swelling,
· Eye problems: macular degeneration (dry and wet), optic neuritis, iritis, deteriorating eye sight, etc.)
· Internal medicine problems: kidney disease, hypertension, hypercholesterinemia, syndrome X
· OB/gyn: difficulties of pregnancy, impotence, uterine fibroids, infertility, etc.
C. Diagnosis:
· History of Exposure: (Did you ever have any amalgam fillings? How much fish do you eat and what kind? A tick bite? etc)
· Symptoms: (How is your short term memory? Do you have areas of numbness, strange sensations,etc)- A complete neurotoxin questionaire is available from AANT@425 462 1777
· Laboratory Testing: direct tests for metals: hair, stool, serum, whole blood, urine analysis,breath analysis
· Xenobiotics: fatty tissue biopsy, urine, breath analysis
· Indirect tests: cholesterol (increased while body is dealing with Hg), increased insulin sensitivity, creatinine clearance, serum mineral levels (distorted, while Hg is an unresolved issue), Apolipoprotein E 2/4, urine dip stick test: low specific gravity (reflects inability of kidneys to concentrate urine), persistently low urine ph (metals only go into solution in acidic environments - which supports detoxing), urine porphyrins
· Autonomic Response Testing: (Dr. Dietrich Klinghardt M.D., Ph.D.)
· BioEnergetic Testing (EAV, kinesiology etc.)
· Response to Therapeutic Trial
· Functional Acuity Contrast Test (measure of Retinal Blood Flow)
· Non-specific neurological tests: upper motor neuron signs (clonus, Babinski, hyperreflexia), abnormal nerve conduction studies, EMG etc . non-specific MRI/CT findings: brain atrophy as in AD, demyelination
· Several ‘challenge tests’ are used today. They generally involve measuring the urine metal content,then administering an oral or iv. mobilizing agent and re-mesuring the metal content in the urine after a few hours. Most well known is the DMPS challenge test: However, there is agreement amongst most researchers, that the urine Hg content does not reflect total body burdon – only the currently mobilizable portion of Hg in the endothelium and kidneys. If nothing comes out, there can still be detrimental but non-responsive amounts of Hg in the CNS, connective tissue and elsewhere.
· I have developed a simple approach that works well. I use autonomic response testing (muscle biofeedback) to determine what metal is stored where and what detox agents would be most suitable for this individual. I obtain a hair sample and have it analyzed. It may or may not show any toxic metals. Metals reach the root of the hair via the blood stream. Hair only can show those metals, that have been in the blood in the last 6 weeks. That means, hair only reflects acute toxicity or recently mobilized metals but not the true body burdon. Then we embark on the detox and mobilizing program. In 6 weeks another hair samle is send to the lab and analyzed. If for example manganese is now high, mercury starting to rise (mostly it is methyl Hg, that is reflected in hair), aluminum is at the same value as before, it means, that this program is starting to mobilize Mn ad Hg, but not Al.

Through minor adjustments and following the client closely, we observe as the levels in the hair may rise for months or years before returning to low or absent levels. That is the end point. At that time biochemical challenges with Ca EDTA, DMPS or DMSA can be valuabe to see if there are still hidden pockets of metals somewhere in the system that have been ovrlooked with the other methods. In general, the hair-mineral analysis is often overinterpreted. Hair minerals are a reflection of the toxic-metal induced distortion in mineral metabolism.

D. Treatment:
Why would we want to treat anyone at all? Is it really needed? Can the body not eliminate these toxins naturally on its own?

First we need to consider a multitude of risk factors, which influence later decisions:
Here is a short list of independent risk factors which can either cause accumulation of metals in an otherwise healthy body - or slow down, or inhibit the bodys own elimination processes.
· Genetics – Several genes are involved in coding for the production of inherent detox mechanisms. Example: ApoE being the major repair protein in neuronal damage and responsible for removing mercury from the intracellular environment.

There are 4 different subtypes, one of them making the individual prone to accumulating Hg: (Danik, M. and Poirier, J. Apolipoprotein E and lipid mobilizatin in neuronal membrane remodeling and its relevance to Alzheimer's disease. In: Brain Lipidsand Disorders in Biological Psychiatry, edited by Skinner, E.R.

Amsterdam:
Elsevier Science, 2002,p.53-66). Also well known and studied are the individual genetic differences in glutathione availability. Several companies in the Integrative Medicine Field are offering genetic testing today. So far my clinical results were not impressive when I based my detox program on genetic testing only.

· prior illnesses (i.e. kidney infections, hepatitis, tonsillitis etc.)
· surgical operations (scars often restrict the detoxifying abilities of whole body sections, such as the tonsillectomy scar with it´s effect on the superior cervical ganglion - restricting lymph drainage and blood flow from the entire cranium)
· medication or ´recreational´ drug use (overwhelming the innate detox mechanisms)
· emotional trauma, especially in early childhood. This issue is huge and almost never appropriately adressed
· social status (poor people may still drink contaminated water)
· high carbohydrate intake combined with protein malnutrition (especially in vegetarians)
· use of homeopathic mercury (may redistribute Hg into deeper tissues)
· food allergies (may block the kidneys, colon etc.)
· the patients electromagnetic environment (mobile phone use, home close to power lines etc.Omura showed that heavy metals in the brain act as micro antennae concentrating damaging electro smog in the brain)
· constipation
· compromise of head/neck lymphatic drainage (sinusitis, tonsil ectomy scars, poor dental occusion)
· number of dental amalgam fillings over the patients life-time, number of the patients mothers amalgam fillings

Detox Methods
There are many considerations in choosing detox agents. After choosing the appropriate agent for the individual client and particular metal and exact chemical form of it, we have to consider the body compartment where the metal is stored.

For example, the algae chlorella is ideal for removing virtually all toxic metals from the gut but has too little effect on mercury stored in the brain. Intravenous glutathione may reach the intracellular environment, even in the brain, but is fairly ineffective in removing mercury from the gut.

Each agent has a primary place of action, which determines when, how much and for how long it is used. Agents that have multiple effects on compounds of different metals in the various body compartments are the basis for our detox program. Most specific agents are used for special situations only.

High protein, mineral, fatty acid and fluid intake
Rationale:
· proteins provide the important precursors to the endogenous metal detox and shuttle agents, such as coeruloplasmin, metallothioneine, glutathione and others. The branched-chain amino acids in cow and goat whey have valuable independent detox effects. Amino acid supplements, especially with a concentrate of brached chain amino acids are valuable.

· Metals attach themselves only in places that are programmed for attachment of metal ions.

Mineral deficiency provides the opportunity for toxic metals to attach themselves to vacant binding sites.

A healthy mineral base is a prerequisite for all metal detox attempts (selenium, zinc, manganese, germanium, molybdenum etc.). Substituting minerals can detoxify the body by itself. Just as important are electrolytes (sodium, potassium, calcium, magnesium), which help to transport toxic waste across the extracellular space towards the lymphatic and venous vessels.

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Chemical & Heavy Metal Cleanse Starter Kit $149.85 [ learn more ] The Chemical & Heavy Metal Starter Kit was designed by Dr. Group for individuals that are new to the cleansing process, or are simply looking for an easy-to-perform, cost effective cleanse program. The Heavy Metal Starter Kit is comprised of LIFE Detox Foot Patches™, NDF Plus™, and Quantum Zeolite™.

Doctor, Am I really Toxic?

May I wish you and your family a prosperous, joyous and healthy New Year! As practitioners, no doubt you often talk about toxicity to your patients. The usual question that I am often asked is: "but how do you know that I am toxic doctor?" Well, unless you have run complex tests on blood, urine and faeces using ICP-MS and GC-MS technology, this is really quite a hard one to answer.

WE ARE ALL TOXIC!
One of the most convincing ways that I have found is to simply say, "but we are all toxic – let me prove it to you!" I then summarize scientific studies that have shown that even newborn babies are toxic with a wide variety of toxins.

Please read the interesting .pdf file entitled BodyBurden: The Pollution in Newborns <http://www.detoxmetals.com/mailing/link.php?id=886e884027> written by the Environmental Working Group in July 2005 - I cetainly found it fascinating and very enlightening.

I have a copy in my waiting room which patients can freely read. In summary, it is a detailed analysis of how blood taken from newborn umbilical cords was shown to contain an average of 287 toxins. Of the 287 chemicals detected, 180 cause cancer in humans or animals, 217 are toxic to the brain and nervous system, and 208 cause birth defects or abnormal development in animal tests.

There are other similar studies that have shown that even blood taken from newborns in Greenland from the Inuit Eskimos are showing levels of mercury, lead, cadmium and even DDT - we all think that the North Pole is squeaky clean, but apparently not!

It is not difficult to extrapolate that if newborn babies just entering this world are so toxic, then certainly we as adults MUST be a lot more toxic. It would not be wrong to say for the majority of people that the longer we are on this planet, the more toxic we will be.

SOLUTION?
So what can we do about it doctor?

Well, first we must develop a "detox consciousness" where we simply accept that we cannot escape from these toxins, whereever we may be on this planet.

Therefore, we need to detoxify in much the same way as we take antixodiants and nutritional supplements to protect us against developing chronic disease.

I usually get most of my patients to follow the "Alkaline Detoxification Diet" <http://www.detoxmetals.com/mailing/link.php?id=886e884024> which is a good, all-body cleanse.

This is usually followed by the Gall Bladder Cleanse <http://www.detoxmetals.com/mailing/link.php?id=886e884026> which is a powerful way of cleaning the liver and toxic bile.

there are two choices – one is to use a synthetic chelator such as DMSA, DMPS or EDTA – I think everyone agrees that these synthetic chelators are quite aggressive and can certainly cause side effects, particularly in children and adults with neurological problems, not to mention the elimination of essential minerals too. So what’s the alternative?

NATURAL CHELATORS?
I would like to bring your attention to a natural heavy metal chelator that is very "gentle" in its action with no side effects. This was a synergistic compound of three natural ingredients, namely Chlorella Growth Factor, Coriandrum sativum and a homaccord of Chlorella vulgaris. None of these individual components worked by themselves when tested in double-blind, placebo controlled trials.

However, when combined, there was a "magic" synergy which showed that this compound could chelate aluminium, antimony, arsenic, cadmium, lead, mercury, nickel, thalium and uranium.

I have attached the double blind, placebo controlled study with 350 people that was conducted on this synergistic formula which is now available to all practitioners who are interested in using natural chelators in their practice. The product is called HMD™ and can certainly be combined with synthetic chelators if one wishes.

ADDITIONAL BENEFITS?
Apart from chelating heavy metals, the HMD™ provides many additional benefits due to its individual components such as a hepato-protective effect, immune modulation, can lower blood sugar, detoxifies other xenobiotics, combats damaging free radicals, enhances production of interferon, accelerates and enhances the re-growth of damaged tissue even when ulcerated, burnt and resistant to other healing modalities, it activates cellular functions and increases metabolism, it normalizes the metabolism of fats, activates protein synthesis and promotes rapid healthy growth in children without adverse side effects.

It also helps to resist the effects of premature aging and encourages the rejuvenation of the body’s own DNA/RNA, thus strengthening and improving hair, skin, and nails.

WHO CAN USE IT?
Basically everyone - even young children with ADHD, autism and other neurological problems that may have been caused by heavy metals. HMD™ can also be used in pre-conceptual care by women considering a child – it can be taken 3-4 months before conception to help reduce the toxic load of the mother. It can be used preventatively for all the family, as well as in cases of known heavy metal toxicity. Basically, everyone should be taking a course as part of their detoxification program at least 3-4 months of each year.

more information's at: chelation


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Chemical & Heavy Metal Cleanse Starter Kit $149.85 [ learn more ] The Chemical & Heavy Metal Starter Kit was designed by Dr. Group for individuals that are new to the cleansing process, or are simply looking for an easy-to-perform, cost effective cleanse program. The Heavy Metal Starter Kit is comprised of LIFE Detox Foot Patches™, NDF Plus™, and Quantum Zeolite™.

Mercury Detoxification Protocol

1. Diet
Avoid all sugar and milk, limit all processed foods and most grains, especially wheat. It will be important to have a high protein diet as the sulfur bearing amino acids in the protein will greatly facilitate detoxification. Do NOT attempt to fast during DMPS mercury detoxification. If you are a vegetarian you will be at HIGH risk for complications from DMPS unless you have a large amount of protein.

Whey protein can be used as a supplement as it is high in glutathione and branched chain amino acids. Two large tablespoons are used per drink and that can be taken once a day and twice a day for the week prior to DMPS chelation.

Autistic children can't use this product as it contains casein. They can use pure branched chain amino acids. You can start with one capsule twice daily and mix with food. Work up to two capsules twice a day for the week prior to DMPS chelation.

2. Beneficial Bacteria
Take one quarter to one half teaspoon once a day of a high potency high quality strain. It is vital to have an optimized bowel flora for detoxification.
3. Maintain two to three bowel movements per day

If you are not having this many bowel movements make certain that your thyroid status has been checked. It is very common for mercury to affect the thyroid. If your thyroid function is fine then you should add some magnesium.

If you are on long-term magnesium it is important to take some calcium with it or after awhile you will develop an imbalance in your calcium magnesium ratio which could result in severe cramping.

• Calcium (Calcium citrate)
• Calcium Gluconate)
• Chelation

Freshly ground flax seed several teaspoons per day will facilitate intestinal movement and also contribute some healthy essential fatty acids.

• Mercury Detoxification Procedures: Amalgam Fillings

4. Unload the connective tissue with Chlorella or ProChitosan
Chlorella and ProChitosan are an important part of the detoxification program, as approximately 90% of the mercury in our bodies is eliminated through the stool. Chlorella is an algae and, unlike Protchitosan, has protein high levels of chlorophyll and other nutrients which can be used for nourishment.

The chlorella powder is the most cost effective approach but some people will prefer the tablets or capsules for convenience. A simple way to dissolve the powder is to place it in a container with a lid partially filled with water. Then tighten the lid and shake to dissolve and drink the solution.

Caution: About 30% of people can't tolerate chlorella. This may be due to optimized function of the enzyme cellulase. If you are unable to tolerate this it would be wise to consider adding an enzyme with cellulase in it to help digest the chlorella.

Dose: One can start out with a one quarter of a teaspoon of the powder (one 500 mg tablet) once a day initially to confirm that there is no hypersensitivity present. Work up slowly over one to two weeks to a dose of one teaspoon (ten tablets or capsules) per day.

Once you tolerate this dose you are able to use it to bind the mercury. Use this dose starting two days prior to your chelation and for one day afterwards. The chlorella will thoroughly coat your intestine and bind like a sponge to any mercury that the DMPS liberates into the gut.

The above dose is based on a 150 pound adult. If you are using the program for children reduce the dose proportionately. (So a 30 pound child would have have 30/150 or 1/5 (20%) of the dose).

Caution: If at any time one develops nausea or starts "burping up" the chlorella taste then the chlorella should be stopped immediately as a food sensitivity is developing which will only worsen if you continue taking it. If this happens you should switch to ProChitosan This binds similarly to mercury. Its dose is dependent on your bowel movements.

• Nausea

If you have one bowel movement a day or less you should start two days prior to the DMPS . If you have two or more bowel movement you can start 24 hours prior to the DMPS. Stay on it for 24 hours after the DMPS. So you will be on it either two or three days. The dose is two capsules three times a day. Be sure to drink it with plenty of water and increase magnesium if constipation develops.

• constipation

Porphrazyme from Biotics Research is another alternative to chlorella that many clinicians have had success with in mercury detoxification.

5. Start Garlic or MSM
It would be wise to start on garlic regularly to enhance sulfur stores. Use the food, rather than the supplement garlic. Try to get in three cloves per day, but decrease the dose if your odor becomes socially offensive.

Again, as indicated in the chlorella section above, children will have proportionately lower doses.
MSM is a form of sulfur which will help your body to remove the mercury. The initial dose is one capsule twice a day. Increase by one capsule a day until you are at three capsules twice a day. If you have root canals and are chronically sick you may want to increase to five capsules three times a day.

6. Start Cilantro
Cilantro will help mobilize mercury out of the tissue so the DMPS can attach to it and allow it to be excreted from the body. The best form of cilantro is a tincture available from Dragon River (505-583-2348).

The dose is one dropper applied on the wrists and rubbed in twice a day for the two weeks preceding the DMPS IV. It is used the morning prior to the DMPS chlelation but can be stopped for the following two weeks. The tincture is also particularly useful for any joint pain and could be rubbed on the joint that is hurting as an alternative.

You can also augment the tincture with using the herb. It is not as potent, but certainly will add to the program. However, like chlorella, many people are sensitive to oral cilantro. So, if you develop any nausea or discomfort after eating cilantro do not use it orally.

7. Mineral Replacement
It is important to have a generally healthy mineral base. The body works better with toxic metals than no metals at all. Enzymes have certain binding sites that require a metal for them to perform their function as a catalyst. When you are deficient in magnesium, sodium, zinc and other minerals, the body does not let go of the toxic metals very easily.

Selenium and zinc are particularly important trace mineral in mercury detoxification and should be used for most people.

Generally the citrate form of minerals works quite nicely unless one has an low blood phosphorous level. It is important to not take copper or iron though unless a clinician has examined a hair analysis and or blood work and recommended these minerals. Thorne Research has Citramins II which is citrated minerals without copper or iron.

Hydrochloric Acid:
If you do not have a sufficient amount of hydrochloric acid secreted by your stomach then it will be very difficult to ionize mineral supplements to absorb them properly. There is a hydrochloric acid reflex present on the lowest rib approximately one inch lateral to the midline. If this area on the rib is tender to palpation there is a strong likelihood the person is deficient in hydrochloric acid and would benefit from supplementation.

This is especially common in individuals over 50 years old, and also in individuals with food allergies. One to six capsules or more of Betaine hydrochloride is generally taken with the first bite of every meal for proper digestive support. The Betaine can be discontinued once the reflex point in non-tender to deep palpation.

Monitoring Your Mineral Dosing
It will be very important to monitor your mineral levels during the detoxification program. This should be done initially and at least every 6-12 weeks. I only recommend two labs to do this work. Trace Elements and Analytical Research as they are the only two labs that do not wash the hair samples prior to analysis.

8. Digestion and Gall Bladder Support for Autism
Liver and gallbladder congestion are major issues in states of toxicity. To insure that your gallbladder bile flow is functional add magnesium taurate or taurine, butyric acid.

• Autism

The dose of the Butyrex initially is 1/8-1/4 of capsule. Gradually increase the dose to 5 capsules 3 times daily. The Butyrex has a offensive odor which is lessened by keeping it in the freezer. Additionally inserting the powder in applesauce, raw honey or elderberry cough syrup may improve compliance.

Digestive enzymes (containing lipase) and CCK (stimulates contraction of the gall bladder. These can be used one hour after meals containing fat. CCK is taken after dinner (high fat meal)
young children 1/4 tablet
older children 1/2 tablet
teenagers 1 tablet
adults 2 to 4 tablets
Your ability to clear toxins will be impaired if you do not have proper fats to support digestive function. Your diet should contain adequate fat from unprocessed pure oils. Omega Nutrition, Flora or Arrowhead Mills
sunflower
safflower
sesame
OR fats naturally found in foods:
seeds
nuts
avocado
free range organic poultry, eggs, or meats

9. Antioxidants
Vitamin C and E. It would be wise to take Unique vitamin E one capsule per day and about 250-500 mg of vitamin C with each meal. If you are exercising aggressively you can take 1000 mg of C 15-30 minutes prior to exercising. It is also wise to consider adding 2-4,000 mg of Vitamin C powder to a half gallon of water and drinking that throughout the day.

It will be VERY important to take 2000 units (typically five of the 400 unit capsules) of vitamin E the day of and the day after the DMPS injection as this will decrease the side effects of the detoxification reaction considerably. You can also take 1-2 grams of vitamin C immediately prior to the DMPS injection.

10. Start Monthly DMPS Injections, Suppositories or Transdermal
You should not have DMPS if you still have amalgam fillings. If they have been removed the injections can be started on a monthly basis. Collection of the urine is then down to analyze how much mercury is being excreted. One must urinate completely prior to the injection.
We perform the analysis at 90 minutes as that is most convenient, but others do four or 24 hour collections. The DMPS injections are generally given about six times or until the level drops into single digits or you are feeling better.

For pediatric patients
Since an IV is such a traumatic event for most children it is probably wise to use a rectal suppository version of DMPS which is available from most compounding pharmacists. Another alternative is to apply the dose transdermally with DMSO. This is very similar to the way that the hormone secretin is being used for many autistic patients.

The dose is 5 mg of DMPS per kg of body weight and is generally given once a month. The urine collection for pediatric patients incorporates a bag to collect the urine for mercury analysis.

CAUTION: It is very important to NEVER receive DMPS injections when you still have mercury fillings in your mouth. DMPS is capable of removing the mercury from the fillings and causing severe complications.

11. DMPS Alternative
Some people do not tolerate DMPS well. This is especially true for those who have damage in the central nervous system, such as those with MS or ALS or children with fragile brain architecture. If this is the case there are several options. PCA (peptid clathrating agent) spray can be used. The dose is 4 sprays under the tongue every day or every other day.

One may use a dipeptide amino acid or mixed mineral succinates such as Champion Nutrition Muscle Nitro.

more information: mercurydetoxification

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Shannon's Story

“Our daughter was born on May 7, 2001. She had a complicated birth where she was born unresponsive and not breathing. A neonatal specialist revived her and intubated her and she was admitted to the Neonatal Intensive Care Unit for seven days.

On day seven, we were ecstatic to bring home our daughter who was delightful, loving and so aware of her world.

Everything went well until we took her to her 8th month checkup. I had been spacing out her vaccinations as a personal choice from research I had done on the subject. At that 8th month visit, she received three vaccinations. Even though I was extremely reluctant, (it's called Mother's intuition), I was assured by her former pediatrician that it was safe and that I would be negligent if I didn't catch her up on her program.

For 24 hours thereafter, she experienced a low-grade fever and she cried unconsolably all night. We noticed that she stopped babbling and imitating speech sounds. She began rocking on all fours on the floor and banging her head in her high chair. We were extremely concerned, so we had her evaluated and she was diagnosed with Autism.

Her new pediatrician, Dr. Mary Megson, specializes in the treatment of Autistic children. She started her on a supplementation program and cod liver oil. My Mom, Grace Macauley, an N.D. in Fredericksburg, VA., had already started her on a gluten, casein and peanut free diet. We also bought organic meats, eggs and produce for everyone in our household to eat. We noticed some improvement but we still had a long way to go in her recovery.

My Mom discovered and started her on a natural chelation product that was made from chlorella and cilantro to chelate heavy metals from her system. She was on that product as well as a foot cream for well over a year with mediocre results.

It was one defining moment when we saw your advertisement for PCA-Rx that turned our world around. Shannon started on the PC3x for two months and then on the PCA-RX for one month. We sent in a urine sample for testing and the results came back that she was excreting 2 1/2 times the normal level of mercury!! Not one of the other products she had taken was even touching the mercury!! We were absolutely amazed as was our pediatrician!!

Shannon started to really make changes. Her vocabulary was increasing daily by leaps and bounds. One afternoon she looked me right in the eyes and told me that she was happy and that she loved me for the very first time!! At her latest appointment with Dr. Megson, the diagnosis was lifted and she can no longer be labeled as Autistic!! We are proud to share that she will soon be going to regular pre-school!!

If it weren't for us seeing that one advertisement of yours, we might have never known of your products!! Boy, are we glad that we did!! Your products are a MIRACLE and I am sharing that with everyone that I meet!! There is no limit to my happiness and willingness to share your product information.

Thank you from the bottom of my heart for helping our family, "get our daughter back!!" - Mary M.”

Benefits of toxic metal removal - with Alzheimer's and Autism testimonies

“I had seen ads for Detoxamin many times in professional journals and although interesting, I was never moved to place an order. It was a personally devastating event that finally got me off the fence and caused me to order.

Several months back, my best friend's dad was scheduled for "routine" bypass surgery. I had known this man for over thirty years and felt almost as if he was a father to me. He did not fare well with the surgery. The bypass procedure loosened arterial plaque causing multiple mini-strokes with dire consequences. It took more than three weeks for the man to regain partial consciousness and another three weeks before he could utter a few words.

Six months has elapsed. He is now bedridden, confined to a nursing home, a paraplegic for all intents and purposes and there is little hope that he will ever come home. MRI of the brain shows several cerebral infarcts.

It was this sad and unfortunate experience that finally caused me to try Detoxamin.

When one sees such a tragedy, one cannot help but ask the question, what would I do in such a situation? Of course, the answer is to never allow a similar situation to arise in the first place.

Time being of the essence, I decided to try chelation therapy with Detoxamin as a preventative and alternative to future bypass surgery, even though I have no symptoms of coronary artery disease at this time.

It was just after one week of using Detoxamin that I began to notice a definite but somewhat unspecific benefit from the product. I just felt better, my mind seemed sharper and I felt a lift in spirits. After two weeks I noticed specific results in the form of marked improvement of chronic bronchitis. Both my lungs and nasal passages were dramatically clearer.

After four weeks chronic muscle pain (fibromyalgia) was reduced by about eighty percent. In about eight weeks I noticed that my feet, which were always ice cold, began to feel warmer.

To the point that I now walk around my home bare-footed, something I've not been able to do for years.

With such astonishingly beneficial results, I decided to put those nearest and dearest to me on Detoxamin. My wife, my brother and his wife, my sister and her husband, my nephew and his wife and several good friends are now experiencing the benefits or Detoxamin. I am also recommending Detoxamin to my patients.

I do not want to suggest that Detoxamin is a panacea for every imaginable chronic health problem but, interestingly, it appears that each individual not only experiences a common benefit but also an individual benefit.

Perhaps this could be explained by the fact that different people may have been exposed to different types of heavy metals settling in different organs of the body, creating different and various symptoms.

Removal of heavy metals from these organs, then, could reduce a myriad of manifestations.

To me, there is no doubt that there are very few who would not benefit from the removal of heavy metals from their bodies with Detoxamin.
The Detoxamin product is truly effective, modestly priced and very safe to use and as such, stands alone in the alternative health care arena.

Thank you for putting this wonderful product within the grasp of many people who otherwise would never have had chelation therapy available to them as an option.

Sincerely, Dr. Robert L. Meliodon, Huntingdon Valley, PA

Testimonies - The Road Back - One Family with Three Autistic Children

Dear Maxam,
With three autistic boys, ages two, four and seven, you can only imagine how challenging it is to find the time to write. Your products have so dramatically affected their health, as well as mine, that I felt inwardly moved to put pen to paper so that our story would be documented.

My blood type is Rh-negative and my husband's is Rh-positive. During all three pregnancies, my doctor administered RhoGam, a vaccine given to Rh-negative mothers, which I now know to be loaded with thimerosal. It was given to me five times total, once each with my oldest and youngest boys, and three times with my middle son who was diagnosed as high functioning autistic. I later discovered that mercury was also present in my breast milk.

My seven year old son, Garrett, seemed normal and healthy at birth. He was later diagnosed as classic ADHD. His behavior was impulsive, he got into fights at school, he demanded attention, and was uncontrollable at home. In addition, he is diagnosed as Celiac and can't tolerate any gluten foods. He also had sleep disturbances, bed wetting, tinnitus and his eyes didn't focus properly. At other times though, he is incredibly clever, intuitive and sensitive. He is a gifted reader and does well on the computer.

Owen, my four year old, is more notably autistic. He was my most troubled pregnancy and his blood type is Rh-negative, the same as mine. When he was born, his body temperature wasn't regulating and he wouldn't nurse for 48 hours. Owen didn't want to be held or massaged. He was jaundiced by the end of his first week. He also had communication difficulties.

Colin is two years old and was born 20 months after Owen. He was always getting sick with ear infections, sinusitis, pneumonia, vomiting, had at least six bleeding, runny stools per day and had a speech delay. He also has quite a list of food allergies, as well as being IGG (immune) deficient.

All three boys had an under active thyroid and two were Celiac (gluten-intolerant). All three have received their childhood vaccinations. Any activity, even simple ones like bathing, triggered meltdowns. I sought out nutritional therapies and spent $15,000 last year just on supplements. We each ingested approximately 35 pills and capsules everyday. I later realized that our bodies had become toxic from all the supplements. Our diet has to be very simple and completely gluten-free and casein-free.

Our staples are rice, chicken, vegetables and some fruits. There's no room for deviation or we will all have severe reactions.

The true blessing came when I discovered the Maxam formulas. These products are the only ones that my boys don't react to. They started on several of the formulas in October of 2004. The changes in our family during this past year are nothing short of a miracle! The boys have experienced a healthy weight gain and muscle tone as their bodies have come back into balance. They never get sick any more and their bowel movements have normalized. Their autistic symptoms are virtually non-existent.

Garrett, my oldest, has been tested by a psychiatrist and has an IQ of 130. My middle son, Owen, is still a tiny bit delayed, but is talking now and has an amazing way of processing information. He's become very social and has learned to ride a bike and recite our phone number. He is now potty trained and has asked to wear "big boy underpants!" Colin, my youngest, is like an electrical engineer. At 2 1/2, he's fascinated with electronics and appliances.
My deepest, heartfelt gratitude to everyone at Maxam for giving us "normalcy" in our lives. For our family, that is a precious gift!

The primary Maxam products taken were BioGuard, Probiotics-Rx, AF-X, PC3x, PCA-Rx and NG-Rx with the later additions of AV-Rx, B-Max, Dia-Cal, PCM-Rx and TRP.
Annie R. Jacksonville, FL

'Gettin It Right In California
We are the parents of a four year old boy, Alex, who was diagnosed with high functioning autism.

The only foods he would eat consisted of brown, crunchy processed foods, french fries and pancakes.

Alex cound not speak well and had a hard time interacting with other children and processing information. Transition was very hard for him and he only liked being inside the house playing with the computer or video games.

But now, thanks to AF-X and PCA-Rx, Alex, to our amazement, is eating grilled chicken, spinach, salmon and many other foods. It is almost as if he woke up and is discovering food for the first time. He interacts with others and loves to play outdoors.

We have been using the PCA-Rx and AF-X for a couple of months now but I saw the change within a couple of weeks. I didn't tell anybody that I was giving Alex these products, and everybody has been telling me how great he is doing, including his teachers.
Thank you so much. I just want to shout out to the world to try these products. They will change your life and the lives of the people you love.Thank You, Thank You
Emily M & FamilyWeed, California

Danny's Mom Is Convinced !!
I have a 2 1/2 year old son who was diagnosed with PDD several months ago. I have him on several different supplements which have all shown minimal benefit. It wasn't until I came across PCA-Rx and NG-Rx that I really saw results by leaps and bounds!

I had been contemplating chelation therapy for a while but was very reluctant to do so because of the potential side effects, plus, I really did not feel it would make much sense to pump my son with MORE drugs. I then was on the generationsrescue website to see if they had any suggestions and that is where I came across PCA-RX. After reading all about it and how safe and effective it was, I decided I absolutely HAD to try this. It was exactly what I was looking for!

My son has been on PCA-Rx for approximately a month now and I saw a change in his mood within days of beginning this product. He didn't seem as irritable as he usually was. Then I decided to try NG-RX since it seemed that lots of parents use both products hand-in-hand. WELL, NG-RX is nothing short of a miracle in my eyes! I ordered the product and had it overnited because I just could not wait to start it, and I received it on Friday mid-morning.

I immediately gave my son two sprays and by that night I saw a HUGE difference in him.
We went to my mother-in-law's house for a visit that evening and we brought my son to the next door neighbor's house because she has a few young children to play with. I could not believe how social my son was. Pre-NG-RX...he would be very aggressive with other children, have very limited interaction, and really kind of go off on his own more than seek to play with others. This time though, he was running around with her children laughing, taking turns going up and down the slide.

What blew me away the most was all the children were sitting down having ice pops and my son has NEVER been interested in them but this time, he wanted what the other children had. The little girl took him by the hand and asked him to sit down with her and gave him an ice pop and he did it!!! This was a HUGE step. I literally could not believe my eyes.

It has now been just over two weeks since he started NG-Rx and is now on eight sprays a day. His language has EXPLODED and he's saying so much more now. Every day he is trying new words. His aggression is virtually non-existent, at least no more than that of an average two year old. He is transitioning almost practically normal now and is just a happier child.

His ABA therapist even said, "In 15 years of working in this field, I have NEVER seen a child progress this quickly.” That is when I knew this stuff is truly a godsend! I have no intention of EVER taking him off of this spray.

Thank you so much Maxam for helping my little boy and for making him a much happier, normal child again!!
Danny's mom

We're Happy In Texas
On November 11, 2003, we began treating our daughter, Juliann, with PC3x and AF-X. We went through two regimens of this, and then followed with two regimens of PCA-Rx and NG-Rx. The four regimens were administered over a period of six months. The following is a list of symptoms and behaviors my daughter showed and exhibited prior to the Rx product treatment:

Lack of eye contact
Lack of social engagement
Lack of appropriate play
Little to no verbal language
Erratic sleeping patterns
No writing ability outside of scribbling
Frequent outbursts during school
Violence toward others, especially teachers
Poor eating habits (crunchy, brown carbohydrates, candy)
Opposed to change in routine/environment
Sensitivity to certain noises/music

By Christmas of 2003, we were already seeing changes for the better. Her eye contact improved and she began following verbal commands. Her teachers continued to report overall improvements on a weekly basis, beginning with her attention and behavior. Her sleeping patterns consistently improved, and her language began to improve as well.

On Mother's Day of 2004, about six months after starting her Rx treatment, Juliann's great-grandmother watched her write her name without being prompted by anyone! Imagine our surprise to see her do this! When we told her teachers what she had done, they told us that they had been trying to get Juliann to write her name, but had been unsuccessful. Later that day she wrote her name again, this time being prompted by her teachers. It was as if someone had flipped the light switch on.

Today, Juliann is 7 years old, and has continued to improve. She speaks to us in short phrases when she wants something, and now role-plays with stuffed animals and dolls - how appropriate! She can write her name fairly well, and follows verbal commands when given, nine out of ten times. She can dress herself, sings her ABC's, and can withstand a change in environment or routine as well as any other child her age. Most importantly, she sleeps through the night, and eats almost anything. We no longer have to make a special meal for her, in addition to what the rest of the family is eating.

I have told all of my family and my friends of the success we have experienced with the Maxam Rx products, and many gasp for air when I tell them of the cost. Speaking as a parent to other parents out there who question whether or not these products are worth the cost, I will always answer with a sound and confident 'yes'. No price is too high to rescue my little girl from the dungeon of heavy metal toxicity many call Autism. Thank you, Maxam, for your innovation, your courage, and your out-of-the-box thinking.
Brian & Bianca, Houston , Tx

Shannon 's Story
Julie,
Thank you for all of your help with Mom's and my queries. It is always a pleasure!!
Our daughter was born on May 7, 2001. She had a complicated birth where she was born unresponsive and not breathing. A neonatal specialist revived her and intubated her and she was admitted to the Neonatal Intensive Care Unit for seven days. On day seven, we were ecstatic to bring home our daughter who was delightful, loving and so aware of her world.
Everything went well until we took her to her 8th month checkup.

I had been spacing out her vaccinations as a personal choice from research I had done on the subject. At that 8th month visit, she received three vaccinations. Even though I was extremely reluctant, (it's called Mother's intuition), I was assured by her former pediatrician that it was safe and that I would be negligent if I didn't catch her up on her program.

For 24 hours thereafter, she experienced a low-grade fever and she cried unconsolably all night. We noticed that she stopped babbling and imitating speech sounds. She began rocking on all fours on the floor and banging her head in her high chair. We were extremely concerned, so we had her evaluated and she was diagnosed with Autism.

Her new pediatrician, Dr. Mary Megson, specializes in the treatment of Autistic children. She started her on a supplementation program and cod liver oil. My Mom, Grace Macauley, an N.D. in Fredericksburg , VA. , had already started her on a gluten, casein and peanut free diet. We also bought organic meats, eggs and produce for everyone in our household to eat. We noticed some improvement but we still had a long way to go in her recovery.

My Mom discovered and started her on a natural chelation product that was made from chlorella and cilantro to chelate heavy metals from her system. She was on that product as well as a foot cream for well over a year with mediocre results.

It was one defining moment when we saw your advertisement for PCA-Rx that turned our world around. Shannon started on the PC3x for two months and then on the PCA-RX for one month. We sent in a urine sample for testing and the results came back that she was excreting 2 1/2 times the normal level of mercury!! Not one of the other products she had taken was even touching the mercury!! We were absolutely amazed as was our pediatrician!!

Shannon started to really make changes. Her vocabulary was increasing daily by leaps and bounds. One afternoon she looked me right in the eyes and told me that she was happy and that she loved me for the very first time!! At her latest appointment with Dr. Megson, the diagnosis was lifted and she can no longer be labeled as Autistic!! We are proud to share that she will soon be going to regular pre-school!!

If it weren't for us seeing that one advertisement of yours, we might have never known of your products!! Boy, are we glad that we did!! Your products are a MIRACLE and I am sharing that with everyone that I meet!! There is no limit to my happiness and willingness to share your product information.
Thank you from the bottom of my heart for helping our family, "get our daughter back!!"
Mary M.

Good News In Washington D.C.
Dear Maxam Labs,
I ordered two products, PCA-Rx and PC3x, to help remove heavy metals. I also decided to try the PCA-Rx on my 2 year old whom I believe is Autistic.
At 2 1/2, Miriam is very unresponsive and has about a one word vocabulary and usually points to what she wants and takes very long naps of 4-6 hours.

My order arrived on Feb. 17, 2005. I gave Miriam two sprays of PCA-Rx and noticed a difference the SAME DAY!

Miriam was much happier the next day and was attempting new words. I have been giving her two sprays a day for three weeks now. She is MUCH more verbal, saying many more words, trying to sing, more outgoing, and sleeps a lot less. Naps are now 2-3 hours, and best of all, she no longer points. I am really amazed at all of her progress in just 3 weeks. I plan to add NG-Rx to her regiment.

Thank you, Christy, for all of your help and information on the ASN/Maxamlab products. I can tell you how pleased I am and the truly lasting positive effects I'm seeing with Miriam.
Yours Truly,A.L. in Washington , DC

Family - And Friends See Strong Results

Dear Julie And Maxam Labs,
My two children and I are both taking a variety of Maxam Products. As are three of my friends and their children or just their children. We have all seen amazing results. Let me share some more details.

In our family, we have been taking Maxam Products since mid-Oct. My 6 yr old Autistic daughter is taking PCA-Rx, Bioguard, Probiotics-Rx & AF-X. We saw notable progress, but it wasn't until she began the AF-X that the WOW! factor came out. I didn't tell her school, therapists or neighbors about it. Since we began taking these, I have had amazing reports almost daily from school. She has gone from saying a handful of words when asked to do so, to talking spontaneously. Clarity came with existing words. She has verbally expressed and vocalized her wants and so many new words, that I've lost track counting. She has been able to put up to two to four words together at a time.

She is raising her hand asking to lead the group in calendar/circle time. She is doing more age appropriate things. Her acquisition of skills is growing quickly. There are just so many things, I could go on.

The one last thing I want to note is with our children there are two types of progress to be noted (1) acquiring new skills/lang/etc (2) elimination of bad habits and behaviors.....and I have to say, we have seen a lot of progress in this area too. Her OCD, temper tantrums, melt downs, aggression and more has significantly been reduced. I am just thrilled with the progress we have seen.

There are a few side effects we have seen but will summarize them in just a minute.

My son, who is 5 yrs old, has had JRA (juvenile rheumatoid arthritis) since he was 2 1/2 years old. He temporarily lost his ability to walk. We have been through a lot with him as well. While we have been able to help him to lead a pretty typical life, he has suffered from arthritis problems. 3-5 mornings a week he would have a hard time getting out of bed and getting started. He also struggled at times with participating in P.E., sports and just playing. He is on Cellaflex, PCA-Rx, Probiotics-Rx, Bioguard and AF-X.

Since being on these products, he has lost a lot of his arthritis pain and can function normally. We have had a few times when he didn't get the Celleflex and the pain came back. I have also seen improved behaviors with him.
I personally don't have a diagnosis, but have the brain fog, chronic sinus infections and I’m exhausted all of the time. Since I've been on Maxam’s products, I have more energy and have been healthier and I have clearer thinking. So what were the negatives?

Well, what we've seen, is you have to go slow and drink a ton of water to flush these things out of your system. We made the mistake of not doing that and saw constipation and I actually developed a cyst in a node in my groin that I saw a doctor for, but by continuing on the products, it was "flushed" out. There were some sore throats and flu like symptoms, but that's about it. I have found Maxam to be amazingly supportive. The products are expensive, but for us, they have been well worth it.

One of my friends began the week before us with herself and 3 kids (all on the spectrum). They are on their own variation of the products and have seen wonderful things as well. The down side to what they saw were some fevers and some flu like symptoms; due to the eradication of the fevers using the AV-Rx.

My other two friends started about 3 weeks to 1 month ago and are seeing great strides in their children as well.

All of our children are as different as different can be, but the bottom line is, we ALL saw significant progress. Can I explain the science behind it? Not really. I too, am just a mom trying to help my children and want to share our experience with the hopes that it can help someone else. There is something valuable in these products.
Michelle P

Beamer's Progress
Hi Julie
It has now been just over 2 months since Beamer started taking AF-X and PCA-Rx.
I have to say when the spray first arrived, and I read I had to spray it under his tongue and have him hold it in his mouth for 2 minutes, I almost cried.

To be so close to something that I believed might help him and not be able to give it to him, was beyond belief. I quickly called your 1-800 number and pleaded for help. How was I going to get an autistic child who was not even 2 yet to co-operate with this method of administration.

I was very relieved to be assured that this was not a worry. As long as I could get the spray in his mouth, that was all I had to do.
Everything I believed would happen has happened. Beamer is a completely different little boy. Before the spray he had no words at all. I had taught him sign language to try and ease his frustration. This was working well, but speech was our goal.

He no longer grits his teeth and grunts. He actually talks, and I mean understandable words. He is not just mirroring our actions, he knows what the words mean, and uses them appropriately.

After about 2 weeks of using the spray the words started. I awoke one morning hearing him call mama over his monitor. It took me a few seconds to realize that it was Beamer calling me. How my heart soared, he knew who I was and he called me. I had a name.

From this point on more and more words followed. I had been using Baby Bumblebee video's with him, and now he lets us know that he has learned everything on them. He knows his whole alphabet, and can say each letter. He knows his colors, he knows his numbers to 12.

Speech was our big goal, but we have seen so many improvements, since starting with the AF-X and PCA-Rx. He plays pretend now. We love to watch him playing with his little plastic Pooh, Tigger and the whole gang and giving Pooh rides on Eyore's back.

He plays with all his little farm animals and makes all the sounds they make. Now when he watches his video's, you see the understanding in his smile's and laughs at the appropriate times I might add.
He no longer only eats round, brown, foods. He is willing to try more and different foods. He even tried celery.

Every day he says many new words. This morning he was playing with his Pooh figurines, and ask for Poohs house. It came so easy to him, he just looked up and said house please. He was playing with Playdough this morning and he and Papa made some balls. He dropped one and couldn't find it, he kept looking and then shouted there it is as plain as could be.

He takes directions now. You can tell him to look behind and he does. If you say it is under the chair he will look for it. If you ask him to get something from another room, he runs off and gets what you have asked for. The other day after watching Beauty and the Beast, he initiated a game of the Beast chasing him. He ran through the house with his little Hot Wheels suitcase of cars, dragging behind him yelling beast, beast, and laughing.

He comes for hugs, for no reason at all. He will be playing and walk over and give us a hug around the legs, just to let us know he cares. I could go on and on, about the changes, but I think I have told you enough to get the message across that he is doing wonderful.

The other night when I tucked him in to bed, as I was leaving I said love you, as I always do, only this time he responded with a love you. I think that says it all. He knows who we are, he knows who he is, he feels emotions, not just anger, and frustration, but happiness and love.

To any one that has doubts if these products work, I say try them you have nothing to lose and a whole new world for your child to gain. I don't know how long he will have to keep using these sprays, but it really doesn't matter. Time is on our side now. We are winning. By the way Beamer is 2 now, and I don't think you could pick him out in a group of children as the one who has a problem.
Thanks for all your help
Heather W

Wonderful Update To 'Beamer's Progress
I just wanted to give you an update on Beamers progress.
He continues to take his AF-X and his PCA-Rx, and he keeps progressing in leaps and bounds.
We had testing done on him by a speech therapist, the test results were amazing. He is now in the 94th percentile group.

Translated that means that only 6% of children his age have a larger vocabulary. 50% is the average range. So his vocabulary is larger by 46% than most normal children. Not bad, considering he was completely non verbal in Sept., that is only 41/2 short months ago, unbelievable.

That is his spoken level, his comprehension level is much higher. He is putting 2 and 3 words together at a time. Not only can we understand him, but so can perfect strangers. Sometimes this leads to a few embarrassing moments, such as when he saw a man in the store with a white beard and he insisted it was Santa. Strangers often comment on just how chatty he is, we just smile and say yes he is, and we love it. His speech therapist,( who he only saw 3 times) feels there is nothing she can offer him, because he is progressing at such a rapid rate.

We have seen great improvements in other areas also. I can't remember when he had his last temper tantrum. We have just returned from a long trip to Florida . His first time since he was 6 months old in an airport and through security (which can be trying to the best of us)and a long flight.

We were prepared for some transition problems, but were very surprised when there were none. We encountered no problems in going from one hotel to another, he settled in with no adjustment problems at all. We had been very apprehensive about this trip, and were just blown away at how easy it was. It was like traveling with a seasoned traveler. He has come a long way from that little boy; it sometimes took us upwards of a half hour to get out of his room.

Since we have been home, we have looked at videos taken of him last summer. I don't think we realized how silent he was. It is quite heart wrenching to watch those videos and know that without the AF-X and the PCA-Rx; he would still be that silent lost little boy. It is with great joy that we move on to the recent video's and listen to him chatter, and watch him play and run from one animal to the next, at Disney's petting zoo, saying gentle, gentle, as he pets the animals. He loves to watch himself on the videos, and comes and asks for Beamer, and then tells you which he wants to see. We have many for him to pick from, all filled with his laughter, and chatty little voice.

The only sad note to all this progress is that we wish that there was some way of getting this information out to more people. It is upsetting to think that there are so many children out there suffering needlessly, because their parents don't know about these wonderful products. We will continue to tell everyone we meet about them. Because we know without them where Beamer would be, sitting silent, emotionless, and sad. How we celebrate every noisy, fun filled day we have with him now.
Thank you again
Heather W

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